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Essential Biochemistry - Enzymes (Section 6 - No. 11)

Which of the following describes the lock-and-key model of enzyme-substrate interaction?
The substrate induces a conformational change in the enzyme.
The enzyme has a flexible active site.
The substrate fits perfectly into the active site.
The enzyme binds to the substrate after a conformational change.

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In the lock-and-key model, the substrate and enzyme fit precisely.

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